师资团队

钟上威

简介

个人简历

北京大学生命科学学院研究员,博士生导师。

 

教育经历

2012 - 2014 , 博士后 , 分子细胞发育生物学系,耶鲁大学
2010 - 2012 , 联合培养博士生 , 分子细胞发育生物学系,耶鲁大学
2007 - 2012 , 理学博士 , 植物学 , 北京大学
2003 - 2007 , 理学学士 , 生物科学 , 武汉大学

 

研究方向

随着中国进入老龄化社会和城镇化发展,农业机械化生产是未来趋势。但是在机械化播种中,由于幼苗出土的整齐性和存活率较低,造成大量种子损失,并严重影响了农作物的精细分布。实验室致力于研究陆生种子植物对于陆地土壤环境的适应性,集中研究植物种子在土壤中萌发,幼苗向上生长破土而出,以及出土后见光变绿存活的分子调控机制。主要研究内容有:
1)不同土壤环境对植物种子萌发,幼苗生长发育及出土存活的调控机理;
2)出土过程中多种环境因子与植物内源激素共同调控幼苗形态建成的分子网络;
3)叶绿素合成,叶绿体发育,与幼苗抗光氧化损伤分子机制;
4)植物感受土壤机械压力(植物触觉)的蛋白质机器以及机械压力调控植物生长发育的信号传导通路。

 

代表性成果

1. Wu Q., Li Y., Lyu M., Luo Y., Shi H., Zhong S.#, Touch-induced seedling morphological changes are determined by ethylene-regulated pectin degradation, Science Advances, 2020, 6 (48), eabc9294.
2. Wu Q., Kuang K., Lyu M., Zhao Y., Li Y., L J., Pan Y., Shi H., Zhong S.#, Allosteric deactivation of PIFs and EIN3 by microProteins in light control of plant development, PNAS, 2020, 117: 18858-18868. (#corresponding author) (该论文被F1000推荐)
3. Yang C.*, Shen W.*, Yang L.*, Sun Y., Li X., Lai M., Wei J., Wang C., Xu Y., Li F., Liang S., Yang C., Zhong S., Luo M.#, Gao C.#, HY5-HDA9 Module Transcriptionally Regulates Plant Autophagy in Response to Light-to-Dark Conversion and Nitrogen Starvation, Molecular Plant, 2020, 13: 515-531. (* equal contribution, #corresponding author)
4. Lyu M.*, Shi H.*, Li Y., Kuang K., Yang Z., Li J., Chen D., Li Y., Kou X., Zhong S.#, Oligomerization and photo-deoligomerization of HOOKLESS1 controls plant differential cell growth, Developmental Cell, 2019, 51: 78-88. (* equal contribution, #corresponding author)
5. Shi H.*, Lyu M.*, Luo Y.*, Liu S.*, Li Y., He H., Wei N., Deng X.W.#, Zhong S.#, Genome-wide regulation of light-controlled seedling morphogenesis by three families of transcription factors, PNAS, 2018,115: 6482-6487. (* equal contribution, #corresponding author)
6. Liu X., Liu R., Li Y., Shen X., Zhong S.#, Shi H.#, EIN3 and PIF3 Form an Interdependent Module that Represses Chloroplast Development in Buried Seedling, Plant Cell, 2017,29: 3051-3067. (#corresponding author)
(该论文为Plant Cell发表当月最受关注的top5文章之一,被选为亮点文章,并发表评述文章做重点推荐,同时被F1000推荐)
7. Liu X., Li Y., Zhong S.#, Interplay between Light and Plant Hormones in the Control of Arabidopsis Seedling Chlorophyll Biosynthesis, Frontiers in Plant Science, 2017, 8: 1433.
8. Shi H.*, Shen X.*, Liu R., Xue C., Wei N., Deng X.W.#, Zhong S.#, The red light receptor phytochrome B directly enhances substrate-E3 ligase interactions to attenuate ethylene responses, Developmental Cell , 2016,39:597-610., (* equal contribution, # corresponding author) (cover story)
(该论文被遴选为当期封面文章,并由国际著名植物学家Jose M. Alonso教授在同期Developmental Cell上撰写评述文章推荐,同时被Science Signaling的Editors` Choice栏目选中发表评述做亮点推荐)

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